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By using comfortable somatosensory stimulation on an area of skin related to the same nerve, but away from the injury, this intense stimulation would over-ride the painful sensations thus reducing the pain

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It seems conceivable that chronic renal impairment may elevate the threshold to induce a GPx3 response and that high-dose selenium supplementation could sufficiently provide the requisite signal in comparison to placebo

As we extend the use of these medicines in new populations, our clinical experience in those populations will be even thinner, said Drucker

PMCID: PMC10798050